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pubmed-article:18544595pubmed:abstractTextListeria monocytogenes and Staphylococcus aureus invade and multiply in THP-1 monocytes. Fluoroquinolones accumulate in these cells, but are less active against intracellular than extracellular forms of L. monocytogenes and S. aureus. We examined whether differentiation of THP-1 monocytes into adherent, macrophage-like cells increases fluoroquinolone uptake and activity.lld:pubmed
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pubmed-article:18544595pubmed:articleTitleContrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes.lld:pubmed
pubmed-article:18544595pubmed:affiliationUnité de pharmacologie cellulaire et moléculaire, Université catholique de Louvain, Bruxelles, Belgium.lld:pubmed
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