| pubmed-article:18534033 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C0920677 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C0011209 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C1549807 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C1706204 | lld:lifeskim |
| pubmed-article:18534033 | lifeskim:mentions | umls-concept:C1555721 | lld:lifeskim |
| pubmed-article:18534033 | pubmed:dateCreated | 2008-6-25 | lld:pubmed |
| pubmed-article:18534033 | pubmed:abstractText | Human immunodeficiency virus type 1 (HIV-1)-based gene delivery systems are popular due to their superior efficiency of transduction of primary cells. However, these systems cannot be readily used for delivery of anti-HIV-1 genes that target constituents of the packaging system itself due to inimical effects on vector titer. Here we describe HIV-1-based packaging systems containing the Rev-response element (RRE), of simian immunodeficiency virus (SIV) in place of the HIV-1 RRE. The SIV RRE-containing packaging systems were used to deliver the anti-Rev gene, Rev M10, into HIV-1 susceptible target cells. | lld:pubmed |
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| pubmed-article:18534033 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18534033 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18534033 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:18534033 | pubmed:issn | 1742-6405 | lld:pubmed |
| pubmed-article:18534033 | pubmed:author | pubmed-author:Srinivasakuma... | lld:pubmed |
| pubmed-article:18534033 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18534033 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:18534033 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18534033 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18534033 | pubmed:pagination | 11 | lld:pubmed |
| pubmed-article:18534033 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:18534033 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18534033 | pubmed:articleTitle | Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes. | lld:pubmed |
| pubmed-article:18534033 | pubmed:affiliation | Division of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA. srinivas.kumar@vanderbilt.edu | lld:pubmed |
| pubmed-article:18534033 | pubmed:publicationType | Journal Article | lld:pubmed |
