| pubmed-article:18522993 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0018042 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0220843 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0032150 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C1425726 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0599894 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C1521840 | lld:lifeskim |
| pubmed-article:18522993 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:18522993 | pubmed:issue | Pt 13 | lld:pubmed |
| pubmed-article:18522993 | pubmed:dateCreated | 2008-6-20 | lld:pubmed |
| pubmed-article:18522993 | pubmed:abstractText | Plasmodium falciparum, the causative agent of malaria, relies on a complex protein-secretion system for protein targeting into numerous subcellular destinations. Recently, a homologue of the Golgi re-assembly stacking protein (GRASP) was identified and used to characterise the Golgi organisation in this parasite. Here, we report on the presence of a splice variant that leads to the expression of a GRASP isoform. Although the first GRASP protein (GRASP1) relies on a well-conserved myristoylation motif, the variant (GRASP2) displays a different N-terminus, similar to GRASPs found in fungi. Phylogenetic analyses between GRASP proteins of numerous taxa point to an independent evolution of the unusual N-terminus that could reflect unique requirements for Golgi-dependent protein sorting and organelle biogenesis in P. falciparum. Golgi association of GRASP2 depends on the hydrophobic N-terminus that resembles a signal anchor, leading to a unique mode of Golgi targeting and membrane attachment. | lld:pubmed |
| pubmed-article:18522993 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18522993 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18522993 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18522993 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18522993 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18522993 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18522993 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18522993 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18522993 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:18522993 | pubmed:issn | 0021-9533 | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:KruegerAndrea... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:CowmanAlan... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:MartiMatthias... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:SpielmannTobi... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:FothBernardo... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:StruckNicole... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:LangerChristi... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:GilbergerTim... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:TreeckMoritzM | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:HaaseSilviaS | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:HerrmannSusan... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:CabreraAna... | lld:pubmed |
| pubmed-article:18522993 | pubmed:author | pubmed-author:EngelbergKlem... | lld:pubmed |
| pubmed-article:18522993 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18522993 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18522993 | pubmed:volume | 121 | lld:pubmed |
| pubmed-article:18522993 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18522993 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18522993 | pubmed:pagination | 2123-9 | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:meshHeading | pubmed-meshheading:18522993... | lld:pubmed |
| pubmed-article:18522993 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18522993 | pubmed:articleTitle | Plasmodium falciparum possesses two GRASP proteins that are differentially targeted to the Golgi complex via a higher- and lower-eukaryote-like mechanism. | lld:pubmed |
| pubmed-article:18522993 | pubmed:affiliation | Bernhard Nocht Institute for Tropical Medicine, Malaria II, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany. | lld:pubmed |
| pubmed-article:18522993 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18522993 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18522993 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18522993 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18522993 | lld:pubmed |
