| pubmed-article:18509658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18509658 | lifeskim:mentions | umls-concept:C0026769 | lld:lifeskim |
| pubmed-article:18509658 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:18509658 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:18509658 | pubmed:dateCreated | 2008-9-11 | lld:pubmed |
| pubmed-article:18509658 | pubmed:abstractText | To describe signal and contrast properties of an isotropic, single-slab 3D dataset [double inversion-recovery (DIR), fluid-attenuated inversion recovery (FLAIR), T2, and T1-weighted magnetization prepared rapid acquisition gradient-echo (MPRAGE)] and to evaluate its performance in detecting multiple sclerosis (MS) brain lesions compared to 2D T2-weighted spin-echo (T2SE). All single-slab 3D sequences and 2D-T2SE were acquired in 16 MS patients and 9 age-matched healthy controls. Lesions were scored independently by two raters and characterized anatomically. Two-tailed Bonferroni-corrected Student's t-tests were used to detect differences in lesion detection between the various sequences per anatomical area after log-transformation. In general, signal and contrast properties of the 3D sequences enabled improved detection of MS brain lesions compared to 2D-T2SE. Specifically, 3D-DIR showed the highest detection of intracortical and mixed WM-GM lesions, whereas 3D-FLAIR showed the highest total number of WM lesions. Both 3D-DIR and 3D-FLAIR showed the highest number of infratentorial lesions. 3D-T2 and 3D-MPRAGE did not improve lesion detection compared to 2D-T2SE. Multi-contrast, isotropic, single-slab 3D MRI allowed an improved detection of both GM and WM lesions compared to 2D-T2SE. A selection of single-slab 3D contrasts, for example, 3D-FLAIR and 3D-DIR, could replace 2D sequences in the radiological practice. | lld:pubmed |
| pubmed-article:18509658 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18509658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18509658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18509658 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18509658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18509658 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:18509658 | pubmed:issn | 0938-7994 | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:GuttmannCharl... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:BarkhofFreder... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:PouwelsPetra... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:MeierDominik... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:GeurtsJeroen... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:VrenkenHugoH | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:RoosendaalSte... | lld:pubmed |
| pubmed-article:18509658 | pubmed:author | pubmed-author:MoraalBastiaa... | lld:pubmed |
| pubmed-article:18509658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18509658 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:18509658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18509658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18509658 | pubmed:pagination | 2311-20 | lld:pubmed |
| pubmed-article:18509658 | pubmed:meshHeading | pubmed-meshheading:18509658... | lld:pubmed |
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| pubmed-article:18509658 | pubmed:meshHeading | pubmed-meshheading:18509658... | lld:pubmed |
| pubmed-article:18509658 | pubmed:meshHeading | pubmed-meshheading:18509658... | lld:pubmed |
| pubmed-article:18509658 | pubmed:meshHeading | pubmed-meshheading:18509658... | lld:pubmed |
| pubmed-article:18509658 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18509658 | pubmed:articleTitle | Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis. | lld:pubmed |
| pubmed-article:18509658 | pubmed:affiliation | Department of Radiology, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. b.moraal@vumc.nl | lld:pubmed |
| pubmed-article:18509658 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18509658 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:18509658 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:18509658 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18509658 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18509658 | lld:pubmed |
