LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.

Source:http://linkedlifedata.com/resource/pubmed/id/18509060

Proc. Natl. Acad. Sci. U.S.A. 2008 Jun 10 105 23 8032-7

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PMID
18509060