| pubmed-article:18504574 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18504574 | lifeskim:mentions | umls-concept:C0337900 | lld:lifeskim |
| pubmed-article:18504574 | lifeskim:mentions | umls-concept:C0024398 | lld:lifeskim |
| pubmed-article:18504574 | lifeskim:mentions | umls-concept:C0024399 | lld:lifeskim |
| pubmed-article:18504574 | lifeskim:mentions | umls-concept:C0017355 | lld:lifeskim |
| pubmed-article:18504574 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:18504574 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:18504574 | pubmed:dateCreated | 2008-7-3 | lld:pubmed |
| pubmed-article:18504574 | pubmed:abstractText | Cynomolgus macaques (Macaca fascicularis) are quickly becoming a useful model for infectious disease and transplantation research. Even though cynomolgus macaques from different geographic regions are used for these studies, there has been limited characterization of full-length major histocompatibility complex (MHC) class I immunogenetics of distinct geographic populations. Here, we identified 48 MHC class I cDNA nucleotide sequences in eleven Indonesian cynomolgus macaques, including 41 novel Mafa-A and Mafa-B sequences. We found seven MHC class I sequences in Indonesian macaques that were identical to MHC class I sequences identified in Malaysian or Mauritian macaques. Sharing of nucleotide sequences between these geographically distinct populations is also consistent with the hypothesis that Indonesia was a source of the Mauritian macaque population. In addition, we found that the Indonesian cDNA sequence Mafa-B7601 is identical throughout its peptide binding domain to Mamu-B03, an allele that has been associated with control of Simian immunodeficiency virus (SIV) viremia in Indian rhesus macaques. Overall, a better understanding of the MHC class I alleles present in Indonesian cynomolgus macaques improves their value as a model for disease research, and it better defines the biogeography of cynomolgus macaques throughout Southeast Asia. | lld:pubmed |
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| pubmed-article:18504574 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18504574 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18504574 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18504574 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18504574 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:18504574 | pubmed:issn | 0093-7711 | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:HughesAustin... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:WisemanRoger... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:O'ConnorDavid... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:BlaskyAlex... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:O'ConnorShelb... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:PendleyChad... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:BeckerEricka... | lld:pubmed |
| pubmed-article:18504574 | pubmed:author | pubmed-author:KarlJulie AJA | lld:pubmed |
| pubmed-article:18504574 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18504574 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:18504574 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18504574 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18504574 | pubmed:pagination | 339-51 | lld:pubmed |
| pubmed-article:18504574 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:meshHeading | pubmed-meshheading:18504574... | lld:pubmed |
| pubmed-article:18504574 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18504574 | pubmed:articleTitle | MHC class I characterization of Indonesian cynomolgus macaques. | lld:pubmed |
| pubmed-article:18504574 | pubmed:affiliation | Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53706, USA. | lld:pubmed |
| pubmed-article:18504574 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18504574 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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