| pubmed-article:18503770 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0015127 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0035687 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0085113 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0015295 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:18503770 | lifeskim:mentions | umls-concept:C1521733 | lld:lifeskim |
| pubmed-article:18503770 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:18503770 | pubmed:dateCreated | 2008-6-16 | lld:pubmed |
| pubmed-article:18503770 | pubmed:abstractText | We have previously identified an ESE in NF1 exon 37 whose disruption by the pathological mutation c.6792C>G caused aberrant splicing. We now investigate the RNA-protein complexes affected by the c.6792C>G mutation observing that this concurrently decreases the affinity for the positive splicing factor YB-1 and increases the affinity for the negative splicing factors, hnRNPA1, hnRNPA2 and a new player in these type of complexes, DAZAP1. Our findings highlight the complexity of the interplay between positive and negative factors in the exon inclusion/skipping outcome. Furthermore, our observations stress the role of a wide genomic context in NF1 exon 37 definition. | lld:pubmed |
| pubmed-article:18503770 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18503770 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503770 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18503770 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:18503770 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:18503770 | pubmed:author | pubmed-author:BurattiEmanue... | lld:pubmed |
| pubmed-article:18503770 | pubmed:author | pubmed-author:BaralleFranci... | lld:pubmed |
| pubmed-article:18503770 | pubmed:author | pubmed-author:SkokoNatasaN | lld:pubmed |
| pubmed-article:18503770 | pubmed:author | pubmed-author:BaralleMarcoM | lld:pubmed |
| pubmed-article:18503770 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18503770 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:18503770 | pubmed:volume | 582 | lld:pubmed |
| pubmed-article:18503770 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18503770 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18503770 | pubmed:pagination | 2231-6 | lld:pubmed |
| pubmed-article:18503770 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:meshHeading | pubmed-meshheading:18503770... | lld:pubmed |
| pubmed-article:18503770 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18503770 | pubmed:articleTitle | The pathological splicing mutation c.6792C>G in NF1 exon 37 causes a change of tenancy between antagonistic splicing factors. | lld:pubmed |
| pubmed-article:18503770 | pubmed:affiliation | International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, Trieste, Italy. | lld:pubmed |
| pubmed-article:18503770 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18503770 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:4763 | entrezgene:pubmed | pubmed-article:18503770 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:18503770 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18503770 | lld:pubmed |
