| pubmed-article:18503510 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18503510 | lifeskim:mentions | umls-concept:C0230445 | lld:lifeskim |
| pubmed-article:18503510 | lifeskim:mentions | umls-concept:C0020225 | lld:lifeskim |
| pubmed-article:18503510 | lifeskim:mentions | umls-concept:C1744681 | lld:lifeskim |
| pubmed-article:18503510 | lifeskim:mentions | umls-concept:C0805348 | lld:lifeskim |
| pubmed-article:18503510 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:18503510 | pubmed:dateCreated | 2008-9-8 | lld:pubmed |
| pubmed-article:18503510 | pubmed:abstractText | Hydranencephaly, the almost complete absence of the cerebral parenchyma, induced by infection with modified live bluetongue virus (BTV) crossing the placenta has previously been reported in sheep and rarely in cattle in the USA and in South Africa. The current study describes 29 cases of hydranencephaly in bovine foetuses and 'dummy' calves up to 3 months of age in Belgium associated with natural BTV serotype 8 infection very early in gestation. Histological examination of the remaining cerebral parenchyma showed moderate to severe atrophy of the neural tissue. The lesions observed support the hypothesis of BTV-induced destruction of precursor cells. However, in several calves a slight infiltration of the walls of venules and arterioles with T lymphocytes (vasculitis) was observed as well, which seems to be responsible for at least some of the lesions. Bluetongue viral RNA was detected in 15 animals using a BTV-specific real-time RT-PCR with a much higher success rate in brain tissues compared with blood and spleen samples. Virus isolation in embryonated eggs was unsuccessful. In conclusion, hydranencephaly in calves can be associated with natural wild-type BTV-8 intra-uterine infection. | lld:pubmed |
| pubmed-article:18503510 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18503510 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503510 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18503510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18503510 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18503510 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:18503510 | pubmed:issn | 1865-1674 | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:DeprezPP | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:De LeeuwII | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:Vandenbussche... | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:ChiesaFF | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:DucatelleRR | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:VercauterenGG | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:MiseNN | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:De ClercqKK | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:Vandemeulebro... | lld:pubmed |
| pubmed-article:18503510 | pubmed:author | pubmed-author:Van der... | lld:pubmed |
| pubmed-article:18503510 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18503510 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:18503510 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18503510 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18503510 | pubmed:pagination | 293-8 | lld:pubmed |
| pubmed-article:18503510 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:meshHeading | pubmed-meshheading:18503510... | lld:pubmed |
| pubmed-article:18503510 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18503510 | pubmed:articleTitle | Bluetongue virus serotype 8-associated congenital hydranencephaly in calves. | lld:pubmed |
| pubmed-article:18503510 | pubmed:affiliation | Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Belgium. | lld:pubmed |
| pubmed-article:18503510 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18503510 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18503510 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18503510 | lld:pubmed |
