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pubmed-article:18496750pubmed:abstractTextTo evaluate the efficacy and safety of erlotinib in advanced breast cancer. Experimental design Multicenter, phase II study of erlotinib (150 mg orally daily). Cohort 1: progression after anthracyclines, taxanes, and capecitabine (n = 47). Cohort 2: progression after >1 chemotherapy for advanced-stage disease (n = 22). Primary endpoint was response rate (World Health Organization criteria). Secondary endpoints were safety, time to progression, and survival.lld:pubmed
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pubmed-article:18496750pubmed:articleTitleEfficacy and safety of erlotinib in patients with locally advanced or metastatic breast cancer.lld:pubmed
pubmed-article:18496750pubmed:affiliationMemorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. dicklerm@mskcc.orglld:pubmed
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