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pubmed-article:18474311pubmed:abstractTextTRA-8 is an agonistic mouse monoclonal antibody that binds to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor 5, which induces apoptosis in cancer cells through a caspase-8-dependent mechanism. We investigated the ability of TRA-8 to augment the radiotherapy (RT) and chemotherapy response of human glioma cells in vitro and in vivo.lld:pubmed
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pubmed-article:18474311pubmed:articleTitleEnhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.lld:pubmed
pubmed-article:18474311pubmed:affiliationDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA. dbmccurdy@uabmc.edulld:pubmed
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