| pubmed-article:18468564 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18468564 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:18468564 | lifeskim:mentions | umls-concept:C0035168 | lld:lifeskim |
| pubmed-article:18468564 | lifeskim:mentions | umls-concept:C1273870 | lld:lifeskim |
| pubmed-article:18468564 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:18468564 | pubmed:issue | 9-10 | lld:pubmed |
| pubmed-article:18468564 | pubmed:dateCreated | 2008-5-12 | lld:pubmed |
| pubmed-article:18468564 | pubmed:abstractText | Declining productivity with decreasing new molecular entity output combined with increased R&D spending is one of the key challenges for the entire pharmaceutical industry. In order to offset decreasing new molecular entity output, life-cycle management activities for established drugs become more and more important to maintain or even expand clinical indication and market opportunities. Life-cycle management covers a whole range of activities from strategic pricing to a next generation product launch. In this communication, we review how research organizations can contribute to successful life-cycle management strategies using phosphodiesterase 5 inhibitors as an example. | lld:pubmed |
| pubmed-article:18468564 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18468564 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18468564 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18468564 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18468564 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18468564 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18468564 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18468564 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18468564 | pubmed:month | May | lld:pubmed |
| pubmed-article:18468564 | pubmed:issn | 1359-6446 | lld:pubmed |
| pubmed-article:18468564 | pubmed:author | pubmed-author:SandnerPeterP | lld:pubmed |
| pubmed-article:18468564 | pubmed:author | pubmed-author:ZiegelbauerKa... | lld:pubmed |
| pubmed-article:18468564 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18468564 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:18468564 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18468564 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18468564 | pubmed:pagination | 457-63 | lld:pubmed |
| pubmed-article:18468564 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:meshHeading | pubmed-meshheading:18468564... | lld:pubmed |
| pubmed-article:18468564 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18468564 | pubmed:articleTitle | Product-related research: how research can contribute to successful life-cycle management. | lld:pubmed |
| pubmed-article:18468564 | pubmed:affiliation | Bayer HealthCare AG, Global Drug Discovery, Germany. peter.sandner@bayerhealthcare.com | lld:pubmed |
| pubmed-article:18468564 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18468564 | pubmed:publicationType | Review | lld:pubmed |
