Linked Life Data

1846372

Source:http://linkedlifedata.com/resource/pubmed/id/1846372

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:1846372rdf:typepubmed:Citationlld:pubmed
pubmed-article:1846372lifeskim:mentionsumls-concept:C0034493lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0242692lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0597357lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C1179122lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0054493lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0220781lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0005495lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0444498lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0740230lld:lifeskim
pubmed-article:1846372lifeskim:mentionsumls-concept:C0220821lld:lifeskim
pubmed-article:1846372pubmed:issue2lld:pubmed
pubmed-article:1846372pubmed:dateCreated1991-2-27lld:pubmed
pubmed-article:1846372pubmed:abstractTextOur previous immunofluorescence studies support the conclusion that the temporal appearance and subcellular distribution of TS28 (a marker of transverse (T) tubules and caveolae in adult skeletal muscle [Jorgensen, A. O., W. Arnold, A. C.-Y. Shen. S. Yuan, M. Gover, and K. P. Campbell, 1990, J. Cell Biol. 110:1173-1185]), correspond very closely to those of T-tubules forming de novo in developing rabbit skeletal muscle (Yuan, S., W. Arnold, and A. O. Jorgensen, 1990, J. Cell Biol. 110:1187-1198). To extend our morphological studies of the biogenesis of T-tubules and triads, the temporal appearance and subcellular distribution of the alpha 1-subunit of the 1,4-dihydropyridine receptor (a marker of the T-tubules and caveolae) was compared to (a) that of TS28; and (b) that of the ryanodine receptor (a marker of the junctional sarcoplasmic reticulum) in rabbit skeletal muscle cells developing in situ (day 19 of gestation to 10 d newborn) by double immunofluorescence labeling. The results presented show that the temporal appearance and relative subcellular distribution of the alpha 1-subunit of the 1,4-dihydropyridine receptor (alpha 1-DHPR) are distinct from those of TS28 at the onset of the biogenesis of T-tubules. Thus, in a particular developing myotube the alpha 1-DHPR appeared before TS28 (secondary myotubes; day 19-24 of gestation). Furthermore, the alpha 1-DHPR was distributed in discrete foci at the outer zone of the cytosol, while TS28 was confined to foci and rod-like structures at the cell periphery. As development proceeded (primary myotubes; day 24 of gestation) approximately 50% of the foci were positively labeled for both TS28 and the alpha 1-DHPR, while approximately 20 and 30% of the foci were uniquely labeled for TS28 and the alpha 1-DHPR, respectively. The foci labeled for both TS28 and the alpha 1-DHPR and the foci uniquely labeled for TS28 were generally confined to the cell periphery, while the foci uniquely labeled for the alpha 1-DHPR were mostly confined to the outer zone of the cytosol. 1-2 d after birth, TS28 was distributed in a chickenwire-like network throughout the cytosol, while the alpha 1-DHPR was confined to cytosolic foci. In contrast, the temporal appearance and subcellular distribution of the alpha 1-DHPR and the ryanodine receptor were very similar, if not identical, throughout all the stages of the de novo biogenesis of T-tubules and triads examined.(ABSTRACT TRUNCATED AT 400 WORDS)lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:languageenglld:pubmed
pubmed-article:1846372pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:citationSubsetIMlld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:1846372pubmed:statusMEDLINElld:pubmed
pubmed-article:1846372pubmed:monthJanlld:pubmed
pubmed-article:1846372pubmed:issn0021-9525lld:pubmed
pubmed-article:1846372pubmed:authorpubmed-author:ArnoldWWlld:pubmed
pubmed-article:1846372pubmed:authorpubmed-author:JorgensenA...lld:pubmed
pubmed-article:1846372pubmed:authorpubmed-author:YuanS HSHlld:pubmed
pubmed-article:1846372pubmed:issnTypePrintlld:pubmed
pubmed-article:1846372pubmed:volume112lld:pubmed
pubmed-article:1846372pubmed:ownerNLMlld:pubmed
pubmed-article:1846372pubmed:authorsCompleteYlld:pubmed
pubmed-article:1846372pubmed:pagination289-301lld:pubmed
pubmed-article:1846372pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:meshHeadingpubmed-meshheading:1846372-...lld:pubmed
pubmed-article:1846372pubmed:year1991lld:pubmed
pubmed-article:1846372pubmed:articleTitleBiogenesis of transverse tubules and triads: immunolocalization of the 1,4-dihydropyridine receptor, TS28, and the ryanodine receptor in rabbit skeletal muscle developing in situ.lld:pubmed
pubmed-article:1846372pubmed:affiliationDepartment of Anatomy, University of Toronto, Canada.lld:pubmed
pubmed-article:1846372pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1846372pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:1846372lld:pubmed
More...