The aac(6')-Ib gene encodes many variants of an aminoglycoside-acetyltransferase enzyme that is responsible for amikacin resistance. Recently, a new variant aac(6')-Ib-cr capable of modifying aminoglycosides and fluoroquinolones has been described. The aim of our study was to observe the appearance and the location of the aac(6')-Ib gene in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae strains.
Service de Bactériologie-Virologie, Hôpital Lariboisière, Assistance Publique Hôpitaux de Paris, Université Paris VII, 2, rue Ambroise Paré, 75475 Paris, France.
