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pubmed-article:18436877pubmed:abstractTextCerebral vasospasm after subarachnoid hemorrhage (SAH) is a major contributor to mortality and morbidity after aneurysm rupture. Recently, R-type voltage-dependent Ca(2+) channel (VDCC) expression has been associated with increased cerebral artery constriction in a rabbit model of SAH. The goal of the present study was to examine whether the blood component oxyhemoglobin (oxyHb) can mimic the ability of SAH to cause R-type VDCC expression in the cerebral vasculature.lld:pubmed
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pubmed-article:18436877pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:18436877pubmed:articleTitleOxyhemoglobin-induced expression of R-type Ca2+ channels in cerebral arteries.lld:pubmed
pubmed-article:18436877pubmed:affiliationDepartment of Pharmacology, University of Vermont College of Medicine, 86 Beaumont Ave, Burlington, VT 05405, USA.lld:pubmed
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pubmed-article:18436877pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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