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pubmed-article:18433471pubmed:abstractTextGenes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between genes. The evolutionary conservation of co-expression between species can be used to predict protein function more reliably than co-expression in a single species. Here we examine whether co-expression across multiple species is also a better prioritizer of disease genes than is co-expression between human genes alone.lld:pubmed
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pubmed-article:18433471pubmed:authorpubmed-author:HuynenMartijn...lld:pubmed
pubmed-article:18433471pubmed:authorpubmed-author:BrunnerHan...lld:pubmed
pubmed-article:18433471pubmed:authorpubmed-author:van...lld:pubmed
pubmed-article:18433471pubmed:authorpubmed-author:OtiMartinMlld:pubmed
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pubmed-article:18433471pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:18433471pubmed:articleTitleConserved co-expression for candidate disease gene prioritization.lld:pubmed
pubmed-article:18433471pubmed:affiliationCentre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Geert Grooteplein 26-28, 6525 GA, Nijmegen, The Netherlands. m.oti@cmbi.ru.nllld:pubmed
pubmed-article:18433471pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18433471pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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