| pubmed-article:18421383 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18421383 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:18421383 | lifeskim:mentions | umls-concept:C2699488 | lld:lifeskim |
| pubmed-article:18421383 | lifeskim:mentions | umls-concept:C0599473 | lld:lifeskim |
| pubmed-article:18421383 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:18421383 | pubmed:dateCreated | 2008-4-18 | lld:pubmed |
| pubmed-article:18421383 | pubmed:abstractText | The straightforward synthesis of both enantiomers of cis-5'-hydroxythalidomide, a major metabolite of thalidomide, has been accomplished by enzymatic kinetic resolution of a racemic substrate catalyzed by Pseudomonas stutzeri lipase TL. cis-5'-Hydroxythalidomide shows resistance to racemization (and epimerization) at physiological pH. A tube formation assay to assess the ability to inhibit angiogenesis revealed that cis-5'-hydroxythalidomides are inactive. | lld:pubmed |
| pubmed-article:18421383 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18421383 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18421383 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18421383 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18421383 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18421383 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18421383 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18421383 | pubmed:month | May | lld:pubmed |
| pubmed-article:18421383 | pubmed:issn | 1477-0520 | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:YamamotoTakes... | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:SummersLinda... | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:NakamuraShuic... | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:ToruTakeshiT | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:ShibataNorioN | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:TakashimaMasa... | lld:pubmed |
| pubmed-article:18421383 | pubmed:author | pubmed-author:MatsunagaNozo... | lld:pubmed |
| pubmed-article:18421383 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18421383 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:18421383 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:18421383 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18421383 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18421383 | pubmed:pagination | 1540-3 | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:meshHeading | pubmed-meshheading:18421383... | lld:pubmed |
| pubmed-article:18421383 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18421383 | pubmed:articleTitle | Enzymatic resolution and evaluation of enantiomers of cis-5'-hydroxythalidomide. | lld:pubmed |
| pubmed-article:18421383 | pubmed:affiliation | Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan. | lld:pubmed |
| pubmed-article:18421383 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18421383 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18421383 | lld:pubmed |
