| pubmed-article:18420612 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18420612 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:18420612 | lifeskim:mentions | umls-concept:C0683150 | lld:lifeskim |
| pubmed-article:18420612 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:18420612 | lifeskim:mentions | umls-concept:C0021665 | lld:lifeskim |
| pubmed-article:18420612 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:18420612 | pubmed:dateCreated | 2008-4-18 | lld:pubmed |
| pubmed-article:18420612 | pubmed:abstractText | The objective of this 5-wk study was to determine dietary effects on plasma concentrations of insulin-like growth factor-I (IGF-I), as well as milk production and milk components in pasture-fed dairy cows. Thirty-two Holstein cows 4 to 5 wk postpartum were randomly assigned to 4 dietary subgroups. Feed was provided twice daily ad libitum at 0900 and 1600 h composed of fresh-cut pasture, meadow hay, and pelleted cereal grain to achieve differing levels of DMI and ME density (LL: 16.6 kg of DMI and 174 MJ of ME; HL: 17.3 kg of DMI and 181.1 MJ of ME; LH: 15.4 kg of DMI and 183.1 MJ of ME; HH: 17.9 kg of DMI and 213.3 MJ of ME, with the first letter indicating DMI and the second ME, and with H indicating high and L indicating low, respectively). The first day cows were placed on their diets was designated d 0. Concentrations of IGF-I were measured in frozen-thawed samples of plasma using a verified ELISA. Dietary treatment had affected plasma concentrations of IGF-I by d 7 with cows on high ME diets having greater IGF-I concentrations at d 14 (83.7 vs. 45.6 ng/mL) than cows on the low ME diets. The level of DMI had less effect on plasma concentrations of IGF-I at d 14 (72.2 vs. 57.1 ng/mL). Dietary treatment effects on these concentrations had stabilized by d 21. Day-to-day variation in mean plasma concentrations of IGF-I within each dietary treatment was low during an intensive period of daily sampling for 14 d (from d 22 to 35). Within-cow day-to-day variation was also low compared with that among cows within the same dietary group and was associated with a high repeatability in the day-to-day concentration of IGF-I in individual cows. Intraclass correlation coefficients for IGF-I ranged from 0.56 (+/- 0.14) to 0.88 (+/- 0.06) with a combined (pooled) value for the 4 subgroups of 0.77 (+/- 0.05). The ME and DMI effects (H vs. L) at d 35 were 79.3 vs. 41.4 and 62.0 vs. 55.7 ng/mL, respectively. Although the ME and DMI differences also affected milk yield and compositional parameters, the effects were not as proportionately great as those measured for IGF-I. Altering the ME or DMI components of the pasture-based diets produced changes in plasma IGF-I concentrations that did not become stabilized for 3 wk, but were then highly repeatable for individual cows within each dietary group. Both observations have relevance to interpreting data related to plasma concentrations of IGF-I in lactating Holstein cows. | lld:pubmed |
| pubmed-article:18420612 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18420612 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18420612 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18420612 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18420612 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18420612 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18420612 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18420612 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18420612 | pubmed:month | May | lld:pubmed |
| pubmed-article:18420612 | pubmed:issn | 1525-3198 | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:MacmillanK... | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:EganA RAR | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:AndersonG AGA | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:RabieeA RAR | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:ObeseF YFY | lld:pubmed |
| pubmed-article:18420612 | pubmed:author | pubmed-author:HumphrysSS | lld:pubmed |
| pubmed-article:18420612 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18420612 | pubmed:volume | 91 | lld:pubmed |
| pubmed-article:18420612 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18420612 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18420612 | pubmed:pagination | 1814-21 | lld:pubmed |
| pubmed-article:18420612 | pubmed:meshHeading | pubmed-meshheading:18420612... | lld:pubmed |
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| pubmed-article:18420612 | pubmed:meshHeading | pubmed-meshheading:18420612... | lld:pubmed |
| pubmed-article:18420612 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18420612 | pubmed:articleTitle | Variation in plasma concentrations of insulin-like growth factor-I in pasture-fed Holstein cows. | lld:pubmed |
| pubmed-article:18420612 | pubmed:affiliation | School of Agriculture and Food Systems, the University of Melbourne, Victoria 3031, Australia. | lld:pubmed |
| pubmed-article:18420612 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18420612 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:18420612 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:18420612 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
