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pubmed-article:18413711pubmed:abstractTextGermline genomic methylation is essential for gamete identity and integrity in mammals. The study by Kuramochi-Miyagawa and colleagues (908-917) in the previous issue of Genes & Development links the process of DNA methylation-dependent repression of retrotranspons with the presence of piwi-interacting RNAs (piRNAs) in fetal male germ cells undergoing de novo methylation.lld:pubmed
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pubmed-article:18413711pubmed:articleTitleSmall RNA guides for de novo DNA methylation in mammalian germ cells.lld:pubmed
pubmed-article:18413711pubmed:affiliationCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.lld:pubmed
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