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pubmed-article:18404036pubmed:abstractTextThe use of prophylactic antibiotics in the surgical treatment of closed long bone fractures is well established. The duration and dosage of prophylaxis, however, vary significantly among surgeons. A systematic review and meta-analysis were performed to determine if multiple-dose perioperative antibiotic prophylaxis is more effective than a single preoperative dose in the prevention of surgical wound infections during the treatment of closed long bone fractures.lld:pubmed
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pubmed-article:18404036pubmed:articleTitleSingle- versus multiple-dose antibiotic prophylaxis in the surgical treatment of closed fractures: a meta-analysis.lld:pubmed
pubmed-article:18404036pubmed:affiliationDepartment of Orthopaedics, University of British Columbia, Vancouver, British Columbia, Canada.lld:pubmed
pubmed-article:18404036pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18404036pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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