Linked Life Data

18398152

Source:http://linkedlifedata.com/resource/pubmed/id/18398152

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pubmed-article:18398152pubmed:abstractTextAZD2171 is a potent inhibitor of vascular endothelial growth factor receptors that showed broad antitumor activity in preclinical models. Doses of up to 45 mg/d of AZD2171 are tolerable when administered alone. This study evaluated escalating doses of AZD2171 in combination with standard chemotherapy in patients with advanced non-small-cell lung cancer.lld:pubmed
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pubmed-article:18398152pubmed:articleTitlePhase I and pharmacokinetic study of daily oral AZD2171, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer: the National Cancer Institute of Canada clinical trials group.lld:pubmed
pubmed-article:18398152pubmed:affiliationThe Ottawa Hospital Cancer Centre, 501 Smyth Road, Ottawa ON K1H 8L6, Canada. slaurie@ottawahospital.on.calld:pubmed
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