The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells.

Source:http://linkedlifedata.com/resource/pubmed/id/18375078

Toxicol. Lett. 2008 Apr 21 178 1 61-9

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18375078