| pubmed-article:1833672 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0042034 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0034929 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0598695 | lld:lifeskim |
| pubmed-article:1833672 | lifeskim:mentions | umls-concept:C0813872 | lld:lifeskim |
| pubmed-article:1833672 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1833672 | pubmed:dateCreated | 1991-10-31 | lld:pubmed |
| pubmed-article:1833672 | pubmed:abstractText | The effects of MK-801 (Dizocilpine) on the micturition reflex were studied in rats anesthetized with urethane (1.2 g/kg, s.c.). MK-801, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist (1-1000 micrograms/kg, i.v.) reduced, in a dose-dependent fashion the amplitude of rhythmic bladder contractions recorded isovolumetrically via a transurethral catheter. The largest doses (300-1000 micrograms/kg) completely abolished bladder activity. Bilateral section of the hypogastric nerves had no effect on MK-801 induced inhibition. MK-801 did not inhibit the bladder contractions induced by electrical stimulation of the pelvic nerve. These data suggest that MK-801 acts in the central nervous system to block glutaminergic excitatory transmission in the central micturition reflex pathway. | lld:pubmed |
| pubmed-article:1833672 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1833672 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1833672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1833672 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1833672 | pubmed:month | May | lld:pubmed |
| pubmed-article:1833672 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:1833672 | pubmed:author | pubmed-author:de GroatW CWC | lld:pubmed |
| pubmed-article:1833672 | pubmed:author | pubmed-author:RoppoloJ RJR | lld:pubmed |
| pubmed-article:1833672 | pubmed:author | pubmed-author:YoshiyamaMM | lld:pubmed |
| pubmed-article:1833672 | pubmed:author | pubmed-author:RihmlandJJ | lld:pubmed |
| pubmed-article:1833672 | pubmed:author | pubmed-author:BlastosBB | lld:pubmed |
| pubmed-article:1833672 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1833672 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:1833672 | pubmed:volume | 126 | lld:pubmed |
| pubmed-article:1833672 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1833672 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1833672 | pubmed:pagination | 141-4 | lld:pubmed |
| pubmed-article:1833672 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:meshHeading | pubmed-meshheading:1833672-... | lld:pubmed |
| pubmed-article:1833672 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1833672 | pubmed:articleTitle | The effects of MK-801, an NMDA receptor antagonist, on the micturition reflex in the rat. | lld:pubmed |
| pubmed-article:1833672 | pubmed:affiliation | Department of Pharmacology, School of Medicine, University of Pittsburgh, PA 15261. | lld:pubmed |
| pubmed-article:1833672 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1833672 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1833672 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1833672 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1833672 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1833672 | lld:pubmed |
