| pubmed-article:18317964 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0025936 | lld:lifeskim |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0678222 | lld:lifeskim |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0596722 | lld:lifeskim |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
| pubmed-article:18317964 | lifeskim:mentions | umls-concept:C0686907 | lld:lifeskim |
| pubmed-article:18317964 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18317964 | pubmed:dateCreated | 2008-3-4 | lld:pubmed |
| pubmed-article:18317964 | pubmed:abstractText | A transgenic mouse model of autochthonous mammary carcinoma was chosen to study the impact of tumor progression on the immune system over an extended period. We found: i) that splenocyte numbers, particularly myeloid cells, increased concurrently with tumor burden; ii) the percentage of tumor-infiltrating Treg cells was similar to that in human breast cancer; iii) suppressed T cell proliferation and cytokine production and; iv) significantly elevated MCP-1 and TNF-alpha in the sera of tumor-bearing mice. The modified immune status in these tumor-bearing hosts is consistent with a "syndrome" that likely impacts the efficacy of cancer immunosurveillance and response to therapy. | lld:pubmed |
| pubmed-article:18317964 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18317964 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18317964 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18317964 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18317964 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18317964 | pubmed:issn | 1532-4192 | lld:pubmed |
| pubmed-article:18317964 | pubmed:author | pubmed-author:LutsiakM E... | lld:pubmed |
| pubmed-article:18317964 | pubmed:author | pubmed-author:AbramsScott... | lld:pubmed |
| pubmed-article:18317964 | pubmed:author | pubmed-author:StewartTrina... | lld:pubmed |
| pubmed-article:18317964 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18317964 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:18317964 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18317964 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18317964 | pubmed:pagination | 237-49 | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:meshHeading | pubmed-meshheading:18317964... | lld:pubmed |
| pubmed-article:18317964 | pubmed:articleTitle | Immune consequences of protracted host-tumor interactions in a transgenic mouse model of mammary carcinoma. | lld:pubmed |
| pubmed-article:18317964 | pubmed:affiliation | Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. | lld:pubmed |
| pubmed-article:18317964 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18317964 | pubmed:publicationType | Research Support, N.I.H., Intramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18317964 | lld:pubmed |
