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pubmed-article:1831488pubmed:abstractTextThe stimuli for the increase in epidermal mitosis during wound healing are not fully known. We construct a mathematical model which suggests that biochemical regulation of mitosis is fundamental to the process, and that a single chemical with a simple regulatory effect can account for the healing of circular epidermal wounds. The numerical results of the model compare well with experimental data. We investigate the model analytically by making biologically relevant approximations. We then obtain travelling wave solutions which provide information about the accuracy of these approximations and clarify the roles of the various model parameters.lld:pubmed
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pubmed-article:1831488pubmed:authorpubmed-author:MurrayJ DJDlld:pubmed
pubmed-article:1831488pubmed:authorpubmed-author:SherrattJ AJAlld:pubmed
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pubmed-article:1831488pubmed:year1991lld:pubmed
pubmed-article:1831488pubmed:articleTitleMathematical analysis of a basic model for epidermal wound healing.lld:pubmed
pubmed-article:1831488pubmed:affiliationCentre for Mathematical Biology, Mathematical Institute, Oxford, UK.lld:pubmed
pubmed-article:1831488pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1831488pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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