| pubmed-article:1826889 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C0598666 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C1524062 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:1826889 | lifeskim:mentions | umls-concept:C1711207 | lld:lifeskim |
| pubmed-article:1826889 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1826889 | pubmed:dateCreated | 1991-5-30 | lld:pubmed |
| pubmed-article:1826889 | pubmed:abstractText | The human T cell receptor (TcR) beta chain gene segment diversity has been studied using the anchored-polymerase chain reaction. Three hundred and fifty C beta-specific transcripts derived from peripheral lymphocytes were analyzed. Transcripts including V-D beta 1-J beta 2-C2 sequences were found with a high frequency (greater than 10%), suggesting that "illegitimate" joinings may constitute a cis-complementing rearrangement mechanism capable of substantially increasing the TcR beta chain combinatorial diversity. Twelve previously undescribed V beta gene segments have been identified. Five of them delineate four novel V beta subfamilies (V beta w21: two members, V beta w22, 23, 24: one member) which all have a murine homologue. The additional seven gene segments belong to the V beta 5, V beta 6, V beta 12 and V beta 13 subfamilies. In addition, the sequences of two known V beta 7 and V beta 9 gene segments have been extended. Together, the present data support the view that the contribution of the beta chain combinatorial diversity to the TcR alpha/beta variability has not yet been fully appreciated. | lld:pubmed |
| pubmed-article:1826889 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1826889 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1826889 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1826889 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1826889 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1826889 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1826889 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1826889 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1826889 | pubmed:issn | 0014-2980 | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:AzocarJJ | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:TriebelFF | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:HercendTT | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:FerradiniLL | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:Roman-RomanSS | lld:pubmed |
| pubmed-article:1826889 | pubmed:author | pubmed-author:MichalakiHH | lld:pubmed |
| pubmed-article:1826889 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1826889 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:1826889 | pubmed:geneSymbol | V beta | lld:pubmed |
| pubmed-article:1826889 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1826889 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1826889 | pubmed:pagination | 935-42 | lld:pubmed |
| pubmed-article:1826889 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1826889 | pubmed:meshHeading | pubmed-meshheading:1826889-... | lld:pubmed |
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| pubmed-article:1826889 | pubmed:meshHeading | pubmed-meshheading:1826889-... | lld:pubmed |
| pubmed-article:1826889 | pubmed:meshHeading | pubmed-meshheading:1826889-... | lld:pubmed |
| pubmed-article:1826889 | pubmed:meshHeading | pubmed-meshheading:1826889-... | lld:pubmed |
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| pubmed-article:1826889 | pubmed:meshHeading | pubmed-meshheading:1826889-... | lld:pubmed |
| pubmed-article:1826889 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1826889 | pubmed:articleTitle | Studies on the human T cell receptor alpha/beta variable region genes. II. Identification of four additional V beta subfamilies. | lld:pubmed |
| pubmed-article:1826889 | pubmed:affiliation | Laboratoire d'Hémato-Immunologie, INSERM U333, Institut Gustave Roussy, Villejuif, France. | lld:pubmed |
| pubmed-article:1826889 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1826889 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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