| pubmed-article:182669 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C0006017 | lld:lifeskim |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C0010454 | lld:lifeskim |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C1749467 | lld:lifeskim |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C0001492 | lld:lifeskim |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:182669 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:182669 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:182669 | pubmed:dateCreated | 1976-11-1 | lld:pubmed |
| pubmed-article:182669 | pubmed:abstractText | Culture medium of exponentially growing Bordetella pertussis (strain 114) contains significant quantities of soluble (100,000 X g for 1 h) adenylate cyclase. The enzyme was purified by chromatography on diethylaminoethyl-cellulose and Sephadex G-200. The purest material yielded a single band on sodium dodecyl sulfate-disc gel electrophoresis. It is heat labile, has a temperature optimum of 30 degrees C, a pH optimum of pH 7 to 8, and a Km for adenosine 5'-triphosphate of 0.4 mM, and requires Mg2+ for maximum activity. The molecular weight, by sodium dodecyl sulfate-disc gel electrophoresis and sucrose density gradient, is approximately 70,000. The enzyme is markedly inhibited by fluoride and weakly inhibited by monovalent salts, but its activity is not altered by alpha-keto acids of nonsubstrate nucleoside triphosphates. Thus, but its presence in the culture supernatant, its smaller molecular weight, and its insensitivity to alpha-keto acids and nucleotides, this enzyme differs from the bacterial adenylate cyclases previously described. | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:language | eng | lld:pubmed |
| pubmed-article:182669 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:182669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:182669 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:182669 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:182669 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:182669 | pubmed:author | pubmed-author:WolfeMM | lld:pubmed |
| pubmed-article:182669 | pubmed:author | pubmed-author:HewlettEE | lld:pubmed |
| pubmed-article:182669 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:182669 | pubmed:volume | 127 | lld:pubmed |
| pubmed-article:182669 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:182669 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:182669 | pubmed:pagination | 890-8 | lld:pubmed |
| pubmed-article:182669 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-F... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-M... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-T... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-M... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-A... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-B... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-S... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-C... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-C... | lld:pubmed |
| pubmed-article:182669 | pubmed:meshHeading | pubmed-meshheading:182669-A... | lld:pubmed |
| pubmed-article:182669 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:182669 | pubmed:articleTitle | Soluble adenylate cyclase from the culture medium of Bordetella pertussis: purification and characterization. | lld:pubmed |
| pubmed-article:182669 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:182669 | lld:pubmed |
