| pubmed-article:18228578 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18228578 | lifeskim:mentions | umls-concept:C0007301 | lld:lifeskim |
| pubmed-article:18228578 | lifeskim:mentions | umls-concept:C0812409 | lld:lifeskim |
| pubmed-article:18228578 | lifeskim:mentions | umls-concept:C1283195 | lld:lifeskim |
| pubmed-article:18228578 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:18228578 | lifeskim:mentions | umls-concept:C1655045 | lld:lifeskim |
| pubmed-article:18228578 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18228578 | pubmed:dateCreated | 2008-2-4 | lld:pubmed |
| pubmed-article:18228578 | pubmed:abstractText | For T(1rho) quantification, a three-dimensional (3D) acquisition is desired to obtain high-resolution images. Current 3D methods that use steady-state spoiled gradient-echo (SPGR) imaging suffer from high SAR, low signal-to-noise ratio (SNR), and the need for retrospective correction of contaminating T(1) effects. In this study, a novel 3D acquisition scheme-magnetization-prepared angle-modulated partitioned-k-space SPGR snapshots (3D MAPSS)-was developed and used to obtain in vivo T(1rho) maps. Transient signal evolving towards the steady-state were acquired in an interleaved segmented elliptical centric phase encoding order immediately after a T(1rho) magnetization preparation sequence. RF cycling was applied to eliminate the adverse impact of longitudinal relaxation on quantitative accuracy. A variable flip angle train was designed to provide a flat signal response to eliminate the filtering effect in k-space caused by transient signal evolution. Experiments in phantoms agreed well with results from simulation. The T(1rho) values were 42.4 +/- 5.2 ms in overall cartilage of healthy volunteers. The average coefficient-of-variation (CV) of mean T(1rho) values (N = 4) for overall cartilage was 1.6%, with regional CV ranging from 1.7% to 8.7%. The fitting errors using MAPSS were significantly lower (P < 0.05) than those using sequences without RF cycling and variable flip angles. | lld:pubmed |
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| pubmed-article:18228578 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18228578 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18228578 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18228578 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18228578 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:18228578 | pubmed:issn | 0740-3194 | lld:pubmed |
| pubmed-article:18228578 | pubmed:author | pubmed-author:MajumdarSharm... | lld:pubmed |
| pubmed-article:18228578 | pubmed:author | pubmed-author:LiXiaojuanX | lld:pubmed |
| pubmed-article:18228578 | pubmed:author | pubmed-author:BusseReed FRF | lld:pubmed |
| pubmed-article:18228578 | pubmed:author | pubmed-author:HanEric TET | lld:pubmed |
| pubmed-article:18228578 | pubmed:copyrightInfo | (c) 2008 Wiley-Liss, Inc. | lld:pubmed |
| pubmed-article:18228578 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18228578 | pubmed:volume | 59 | lld:pubmed |
| pubmed-article:18228578 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18228578 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18228578 | pubmed:pagination | 298-307 | lld:pubmed |
| pubmed-article:18228578 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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| pubmed-article:18228578 | pubmed:meshHeading | pubmed-meshheading:18228578... | lld:pubmed |
| pubmed-article:18228578 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18228578 | pubmed:articleTitle | In vivo T(1rho) mapping in cartilage using 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS). | lld:pubmed |
| pubmed-article:18228578 | pubmed:affiliation | Musculoskeletal Quantitative Imaging Research, Department of Radiology, University of California-San Francisco, 185 Berry Street, San Francisco, CA 94107, USA. xiaojuan.li@radiology.ucsf.edu | lld:pubmed |
| pubmed-article:18228578 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18228578 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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