| pubmed-article:18218845 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18218845 | lifeskim:mentions | umls-concept:C0011334 | lld:lifeskim |
| pubmed-article:18218845 | lifeskim:mentions | umls-concept:C0221198 | lld:lifeskim |
| pubmed-article:18218845 | lifeskim:mentions | umls-concept:C1273870 | lld:lifeskim |
| pubmed-article:18218845 | lifeskim:mentions | umls-concept:C1280519 | lld:lifeskim |
| pubmed-article:18218845 | lifeskim:mentions | umls-concept:C0729415 | lld:lifeskim |
| pubmed-article:18218845 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18218845 | pubmed:dateCreated | 2008-1-25 | lld:pubmed |
| pubmed-article:18218845 | pubmed:abstractText | A barrier to providing sealants is concern about inadvertently sealing over caries. This meta-analysis examined the effectiveness of sealants in preventing caries progression. We searched electronic databases for comparative studies examining caries progression in sealed permanent teeth. We used a random-effects model to estimate percentage reduction in the probability of caries progression in sealed vs. unsealed carious teeth. Six studies, including 4 randomized-controlled trials (RCT) judged to be of fair quality, were included in the analysis (384 persons, 840 teeth, and 1090 surfaces). The median annual percentage of non-cavitated lesions progressing was 2.6% for sealed and 12.6% for unsealed carious teeth. The summary prevented fraction for RCT was 71.3% (95%CI: 52.8%-82.5, no heterogeneity) up to 5 years after placement. Despite variation among studies in design and conduct, sensitivity analysis found the effect to be consistent in size and direction. Sealing non-cavitated caries in permanent teeth is effective in reducing caries progression. | lld:pubmed |
| pubmed-article:18218845 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18218845 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18218845 | pubmed:citationSubset | D | lld:pubmed |
| pubmed-article:18218845 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18218845 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18218845 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18218845 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18218845 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:18218845 | pubmed:issn | 0022-0345 | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:BaderJJ | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:RozierR GRG | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:WeintraubJ... | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:MeyerD MDM | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:KohlUU | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:ZernD SDS | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:ClarksonJJ | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:FontanaM RMR | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:GoochB FBF | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:MetzK WKW | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:GriffinS OSO | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:VidakovicBB | lld:pubmed |
| pubmed-article:18218845 | pubmed:author | pubmed-author:CDC Dental... | lld:pubmed |
| pubmed-article:18218845 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18218845 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:18218845 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18218845 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18218845 | pubmed:pagination | 169-74 | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:meshHeading | pubmed-meshheading:18218845... | lld:pubmed |
| pubmed-article:18218845 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18218845 | pubmed:articleTitle | The effectiveness of sealants in managing caries lesions. | lld:pubmed |
| pubmed-article:18218845 | pubmed:affiliation | Centers for Disease Control and Prevention/Division of Oral Health/Surveillance, Investigations, and Research Branch, Chamblee, GA 30341, USA. sig1@cdc.gov | lld:pubmed |
| pubmed-article:18218845 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18218845 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:18218845 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:18218845 | pubmed:publicationType | Meta-Analysis | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18218845 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18218845 | lld:pubmed |
