| pubmed-article:18214174 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C0085494 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C0012652 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:18214174 | lifeskim:mentions | umls-concept:C1522538 | lld:lifeskim |
| pubmed-article:18214174 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:18214174 | pubmed:dateCreated | 2008-1-24 | lld:pubmed |
| pubmed-article:18214174 | pubmed:abstractText | Linezolid was approved in 2000 for treatment of gram-positive coccal infections. We performed a case-control study during a hospital outbreak of linezolid-resistant enterococci (LRE) infections, comparing cases of LRE infection (cases) with linezolid-sensitive enterococci infections (controls). Nasal and perirectal swab samples were obtained from all patients in a 1-day point-prevalence survey. We examined antimicrobial drug use and calculated the defined daily dose of linezolid per 1,000 patient-days. Fifteen LRE cases were identified (13 Enterococcus faecalis and 2 E. faecium); 7 were vancomycin-resistant. Compared with controls, case-patients had increased in-hospital mortality rates and lengths of stay. Multivariate analysis identified independent predictors of LRE infection: prior cultures positive for methicillin-resistant Staphylococcus aureus (adjusted odds ratio [AOR] 27), hospitalization duration before index culture (AOR 1.1 per day), and duration of preceding linezolid therapy (AOR 1.1 per day). Linezolid exposure and patient-to-patient transmission appear to be responsible for LRE infections, an important emeraina hospital problem. | lld:pubmed |
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| pubmed-article:18214174 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18214174 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18214174 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:18214174 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18214174 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:18214174 | pubmed:issn | 1080-6040 | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:JonesTimothy... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:SchaffnerWill... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:SimmonsBryan... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:MeltonKelleyK | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:CraigAllen... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:KainerMarion... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:MooreKelly... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:ChowSusanS | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:DevasiaRose... | lld:pubmed |
| pubmed-article:18214174 | pubmed:author | pubmed-author:BroylesJoyceJ | lld:pubmed |
| pubmed-article:18214174 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18214174 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:18214174 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18214174 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18214174 | pubmed:pagination | 1024-30 | lld:pubmed |
| pubmed-article:18214174 | pubmed:dateRevised | 2010-9-21 | lld:pubmed |
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| pubmed-article:18214174 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:18214174 | pubmed:articleTitle | Response to emerging infection leading to outbreak of linezolid-resistant enterococci. | lld:pubmed |
| pubmed-article:18214174 | pubmed:affiliation | Tennessee Department of Health, Communicable and Environmental Disease Services, Nashville, Tennessee 37243, USA. marion.kainer@state.tn.us | lld:pubmed |
| pubmed-article:18214174 | pubmed:publicationType | Journal Article | lld:pubmed |
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