| pubmed-article:18213520 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18213520 | lifeskim:mentions | umls-concept:C0917725 | lld:lifeskim |
| pubmed-article:18213520 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18213520 | pubmed:dateCreated | 2008-4-14 | lld:pubmed |
| pubmed-article:18213520 | pubmed:abstractText | An important element of artificial skin is a tissue scaffold that allows for fast host regeneration. We present a microfabrication strategy, based on gelling collagen-based components inside a microfluidic device, that produces well-controlled pore sizes inside the scaffold. This strategy can produce finely patterned tissue scaffolds of clinically relevant dimensions suitable for surgical handling. Compared to porous collagen-based sponges produced by lyophilization, microfabricated tissue scaffolds preserve the fibrous structure and ligand density of natural occurring collagen. A fibroblast migration assay revealed fast cellular migration through the pores, which is desired for rapid tissue ingrowth. Finally, we also demonstrate a strategy to use this microfabrication technique to build anatomically accurate, multi-component skin substitutes in a cost-effective manner. | lld:pubmed |
| pubmed-article:18213520 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18213520 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18213520 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18213520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18213520 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18213520 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18213520 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:18213520 | pubmed:issn | 1387-2176 | lld:pubmed |
| pubmed-article:18213520 | pubmed:author | pubmed-author:SiaSamuel KSK | lld:pubmed |
| pubmed-article:18213520 | pubmed:author | pubmed-author:ChinCurtis... | lld:pubmed |
| pubmed-article:18213520 | pubmed:author | pubmed-author:KhannaKrishnK | lld:pubmed |
| pubmed-article:18213520 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18213520 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:18213520 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18213520 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18213520 | pubmed:pagination | 459-67 | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:meshHeading | pubmed-meshheading:18213520... | lld:pubmed |
| pubmed-article:18213520 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18213520 | pubmed:articleTitle | A microfabricated porous collagen-based scaffold as prototype for skin substitutes. | lld:pubmed |
| pubmed-article:18213520 | pubmed:affiliation | Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Ave, New York, NY, 10027, USA. | lld:pubmed |
| pubmed-article:18213520 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18213520 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18213520 | lld:pubmed |
