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pubmed-article:18206478pubmed:abstractTextTrichostatin A (TSA) is a potent histone deacetylase inhibitor and has demonstrated significant antitumor activity against a variety of cancer cell lines. Type I interferons have also shown significant antitumor as well as antiangiogenic activity. In this study, we examined the effectiveness of combination therapy of TSA and interferon beta (IFN-beta) on human neuroblastoma cells in vitro and in vivo using a murine model of retroperitoneal neuroblastoma.lld:pubmed
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pubmed-article:18206478pubmed:pagination177-82; discussion 182-3lld:pubmed
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pubmed-article:18206478pubmed:articleTitleThe efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma.lld:pubmed
pubmed-article:18206478pubmed:affiliationDepartment of Surgery, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.lld:pubmed
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