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pubmed-article:18188557pubmed:abstractTextAlzheimer's disease (AD) is a very complex neurodegenerative disorder, the exact cause of which is still not known. The major histopathological features, amyloid plaques and neurofibrillary tangles, already described by Alois Alzheimer, have been the focus in research for decades. Despite a probable whole cascade of events in the brain leading to impairment of cognition, amyloid is still the target for diagnosis and treatment.lld:pubmed
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pubmed-article:18188557pubmed:articleTitleAmyloid plaque imaging in vivo: current achievement and future prospects.lld:pubmed
pubmed-article:18188557pubmed:affiliationKarolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Alzheimer Neurobiology, Karolinska University Hospital Huddinge, Novum 5th floor, Stockholm, Sweden. Agneta.K.Nordberg@ki.selld:pubmed
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