| pubmed-article:18184439 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C0006142 | lld:lifeskim |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C0043210 | lld:lifeskim |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C0949335 | lld:lifeskim |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C1514559 | lld:lifeskim |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C1704824 | lld:lifeskim |
| pubmed-article:18184439 | lifeskim:mentions | umls-concept:C2826293 | lld:lifeskim |
| pubmed-article:18184439 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:18184439 | pubmed:dateCreated | 2008-4-25 | lld:pubmed |
| pubmed-article:18184439 | pubmed:abstractText | Breast cancer patients with HER2/neu overexpression have poor outcomes with a decrease in disease-free survival (DFS) and overall survival. The biology of HER2/neu overexpression in breast tumors in African-American and Latina women is poorly understood. The purpose of this study is to understand the clinical significance of activated Akt (phospho-Akt or pAkt) expression in breast tumors from African-American and Latina patients with corresponding tissue HER2/neu overexpression. Cellular and molecular studies have shown that activation of the cell signaling phosphatidylinositol-3-kinase/Akt cascade via the HER2/neu and other receptor tyrosine kinases induces cell proliferation. | lld:pubmed |
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| pubmed-article:18184439 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18184439 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18184439 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:18184439 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18184439 | pubmed:issn | 1465-542X | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:VadgamaJaydut... | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:WuYanyuanY | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:ChillarRamR | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:SlamonDennisD | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:MohamedHezlaH | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:ClaytonSheila... | lld:pubmed |
| pubmed-article:18184439 | pubmed:author | pubmed-author:AliIshratI | lld:pubmed |
