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pubmed-article:18092886pubmed:abstractTextAvailability of an ultra-short-course drug regimen capable of curing patients with tuberculosis in 2 to 3 mo would significantly improve global control efforts. Because immediate prospects for novel treatment-shortening drugs remain uncertain, we examined whether better use of existing drugs could shorten the duration of treatment. Rifapentine is a long-lived rifamycin derivative currently recommended only in once-weekly continuation-phase regimens. Moxifloxacin is an 8-methoxyfluoroquinolone currently used in second-line regimens.lld:pubmed
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pubmed-article:18092886pubmed:articleTitleDaily dosing of rifapentine cures tuberculosis in three months or less in the murine model.lld:pubmed
pubmed-article:18092886pubmed:affiliationCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.lld:pubmed
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