| pubmed-article:18088573 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0042036 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0302908 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0026755 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0368608 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0037813 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:18088573 | lifeskim:mentions | umls-concept:C0386776 | lld:lifeskim |
| pubmed-article:18088573 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18088573 | pubmed:dateCreated | 2008-7-22 | lld:pubmed |
| pubmed-article:18088573 | pubmed:abstractText | Due to its increased concentration in blood, 3-hydroxyisovalerylcarnitine (C5OH-I) is an important indicator for the diagnosis of organic acidemias in newborns. However, C5OH-I has not been used as a standard in tandem mass spectrometric (MS/MS) assays because its isolation is difficult. We developed a new synthesis of C5OH-I and investigated its behavior by MS/MS. A method using the multiple reaction monitoring (MRM) mode of MS/MS with HPLC was developed which provides high accuracy, precision and reproducibility. Acylcarnitine profiles in the serum and urine of a patient with multiple carboxylase deficiency (MCD) showed increased levels compared to a healthy patient. | lld:pubmed |
| pubmed-article:18088573 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18088573 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18088573 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18088573 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18088573 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18088573 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18088573 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:18088573 | pubmed:issn | 1570-0232 | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:NakajimaYokoY | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:TogariHajimeH | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:MaedaYasuhiro... | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:ItoTetsuyaT | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:SugiyamaNaruj... | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:KuronoYukihis... | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:UetaAkihitoA | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:YokoiKyokoK | lld:pubmed |
| pubmed-article:18088573 | pubmed:author | pubmed-author:OhmiHironoriH | lld:pubmed |
| pubmed-article:18088573 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18088573 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:18088573 | pubmed:volume | 870 | lld:pubmed |
| pubmed-article:18088573 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18088573 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18088573 | pubmed:pagination | 154-9 | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:meshHeading | pubmed-meshheading:18088573... | lld:pubmed |
| pubmed-article:18088573 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18088573 | pubmed:articleTitle | Determination of 3-hydroxyisovalerylcarnitine and other acylcarnitine levels using liquid chromatography-tandem mass spectrometry in serum and urine of a patient with multiple carboxylase deficiency. | lld:pubmed |
| pubmed-article:18088573 | pubmed:affiliation | Laboratory of Hospital Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan. maeda@phar.nagoya-cu.ac.jp | lld:pubmed |
| pubmed-article:18088573 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18088573 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
