pubmed-article:18082657 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C0000970 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C0048047 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C0201699 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C1705957 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
pubmed-article:18082657 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
pubmed-article:18082657 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:18082657 | pubmed:dateCreated | 2007-12-17 | lld:pubmed |
pubmed-article:18082657 | pubmed:abstractText | Capability of fast analysis of a novel miniaturized capillary electrophoresis with carbon disk electrode amperometric detection (mini-CE-AD) system was demonstrated by determining acetaminophen and p-aminophenol in dosage forms. Factors influencing the separation and detection processes were examined and optimized. Under the optimum conditions, the end-capillary 300 microm carbon disc electrode amperometric detector offered favorable signal-to-noise characteristics at a relatively low potential (+600 mV versus Ag/AgCl) for detecting acetaminophen and p-aminophenol. Two analytes can been separated within 150 s in a 8.5 cm length capillary at a separation voltage of 2000V using a Na2B4O7-KH2PO4 running buffer (pH 7.2). Acetaminophen and p-aminophenol could be detected down to the 1.4 x 10(-6)-5.9 x 10(-7) molL(-1) level with linearity up to the 1.0 x 10(-3) molL(-1) level examined. The inter-day repeatability for analytes in peak current (R.S.D.< or =2.3%) and migration times (R.S.D.< or =1.3%) were excellent. The proposed mini-CE-AD system should find a wide range of analytical applications in pharmaceutical formulations as an alternative to conventional CE and mu-CE. | lld:pubmed |
pubmed-article:18082657 | pubmed:language | eng | lld:pubmed |
pubmed-article:18082657 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18082657 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:18082657 | pubmed:month | Jan | lld:pubmed |
pubmed-article:18082657 | pubmed:issn | 1873-4324 | lld:pubmed |
pubmed-article:18082657 | pubmed:author | pubmed-author:YeJiannongJ | lld:pubmed |
pubmed-article:18082657 | pubmed:author | pubmed-author:ChuQingcuiQ | lld:pubmed |
pubmed-article:18082657 | pubmed:author | pubmed-author:TianXiuhuiX | lld:pubmed |
pubmed-article:18082657 | pubmed:author | pubmed-author:JiangLianmeiL | lld:pubmed |
pubmed-article:18082657 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:18082657 | pubmed:day | 14 | lld:pubmed |
pubmed-article:18082657 | pubmed:volume | 606 | lld:pubmed |
pubmed-article:18082657 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:18082657 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:18082657 | pubmed:pagination | 246-51 | lld:pubmed |
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pubmed-article:18082657 | pubmed:year | 2008 | lld:pubmed |
pubmed-article:18082657 | pubmed:articleTitle | Rapid determination of acetaminophen and p-aminophenol in pharmaceutical formulations using miniaturized capillary electrophoresis with amperometric detection. | lld:pubmed |
pubmed-article:18082657 | pubmed:affiliation | Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, PR China. | lld:pubmed |
pubmed-article:18082657 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:18082657 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18082657 | lld:pubmed |