To test the hypothesis that the identification of mutation in the carboxypeptidase E (CPE) gene which leads to marked hyperproinsulinaemia is consistent with a possible role for mutations in CPE in the development of coronary atherosclerosis.
Department of Cardiovascular Medicine, the first affiliated hospital of Nanjing Medical University, Guangzhou road 300, Nanjing 210029, Jiangsu Province, China. enzhijia@yahoo.com.cn
