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pubmed-article:18077140pubmed:abstractText1 alpha,25-Dihydroxyvitamin D3 (1 alpha,25(OH)2D3), the active form of vitamin D, suppresses keratinocyte proliferation, promotes keratinocyte differentiation, and induces involucrin expression. Peroxisome proliferation-activated receptors (PPARs) are ligand-activated transcription factors. It has been reported that PPARs stimulate keratinocyte differentiation and regulate the expression of differentiation molecules.lld:pubmed
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pubmed-article:18077140pubmed:articleTitlePPAR gamma is an important transcription factor in 1 alpha,25-dihydroxyvitamin D3-induced involucrin expression.lld:pubmed
pubmed-article:18077140pubmed:affiliationDepartment of Dermatology, Ehime University School of Medicine, Ehime, Japan.lld:pubmed
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