| pubmed-article:18055506 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18055506 | lifeskim:mentions | umls-concept:C0017256 | lld:lifeskim |
| pubmed-article:18055506 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:18055506 | pubmed:dateCreated | 2008-1-4 | lld:pubmed |
| pubmed-article:18055506 | pubmed:abstractText | We describe a system for directed evolution based on in vitro compartmentalisation in which amplification of a gene is coupled to the formation of product by the enzyme it encodes. This approach mimics the process of natural selection; 'fitter' genes--encoding more efficient enzymes--have more 'offspring'. It allows selection for any activity so long as a product-specific ligand (e.g. an antibody) is available. | lld:pubmed |
| pubmed-article:18055506 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18055506 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18055506 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18055506 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:18055506 | pubmed:issn | 1741-0126 | lld:pubmed |
| pubmed-article:18055506 | pubmed:author | pubmed-author:GriffithsAndr... | lld:pubmed |
| pubmed-article:18055506 | pubmed:author | pubmed-author:KellyBernard... | lld:pubmed |
| pubmed-article:18055506 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18055506 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:18055506 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18055506 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18055506 | pubmed:pagination | 577-81 | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:meshHeading | pubmed-meshheading:18055506... | lld:pubmed |
| pubmed-article:18055506 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:18055506 | pubmed:articleTitle | Selective gene amplification. | lld:pubmed |
| pubmed-article:18055506 | pubmed:affiliation | Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK. | lld:pubmed |
| pubmed-article:18055506 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18055506 | lld:pubmed |
