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pubmed-article:18050197pubmed:abstractTextInterferon regulatory factor 5 (IRF-5) is a transcription factor involved in the regulation of the host defense. Previous studies have demonstrated a significant association of various IRF5 gene polymorphisms with systemic lupus erythematosus (SLE) in Caucasians. The purpose of this case-control study was to investigate whether IRF5 polymorphisms are involved in the genetic predisposition to primary Sjögren's syndrome (SS), an autoimmune disease closely related to SLE.lld:pubmed
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pubmed-article:18050197pubmed:articleTitleAssociation of an IRF5 gene functional polymorphism with Sjögren's syndrome.lld:pubmed
pubmed-article:18050197pubmed:affiliationINSERM U802, Université Paris-Sud 11, Hôpital Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin Bicêtre, France.lld:pubmed
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