Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc.

Source:http://linkedlifedata.com/resource/pubmed/id/18045875

J. Biol. Chem. 2008 Feb 1 283 5 2724-33

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PMID
18045875