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pubmed-article:18044909pubmed:abstractTextA highly selective oxidative [3 + 2] cycloaddition of chiral enol ethers and hydroxynaphthoquinone is described. This convergent strategy is amenable to an enantioselective synthesis of beta-rubromycin and related naphthoquinone spiroketals. Several compounds were found to inhibit DNA-polymerase and telomerase in a manner resembling alpha-rubromycin and beta-rubromycin.lld:pubmed
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pubmed-article:18044909pubmed:authorpubmed-author:WuKun-LiangKLlld:pubmed
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pubmed-article:18044909pubmed:articleTitleFacile synthesis of naphthoquinone spiroketals by diastereoselective oxidative [3 + 2] cycloaddition.lld:pubmed
pubmed-article:18044909pubmed:affiliationDepartment of Chemistry and Biochemistry, University of California at Santa Barbara, Santa Barbara, California 93106-9510, USA.lld:pubmed
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