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pubmed-article:18040821pubmed:abstractTextThe goal of this component of the meeting was to discuss novel therapeutics that attenuate inflammatory pathways, enhance drug delivery into the brain and/or bypass the blood-brain barrier (BBB). Presentations included discussions of (i) antiretroviral drugs packaged into nanoparticles by Howard Gendelman, (ii) how to engage the nasal epithelium and its closely associated neural fibers as a route for drug entry to the brain, by William H. Frey and Lynn Pulliam, and (iii) antioxidant gene delivery to neurons using vector systems that can protect neurons against HIV-associated toxicity, by David Strayer. The session was capped by active discourse among leaders in the field of adjunctive therapies in a broad range of scientific disciplines.lld:pubmed
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pubmed-article:18040821pubmed:articleTitleTranslational research models and novel adjunctive therapies for neuroAIDS.lld:pubmed
pubmed-article:18040821pubmed:affiliationDepartment of Molecular and Comparative Pathobiology, Johns Hopkins Medicine, Broadway Research Building, Suite 839,733 North Broadway, Baltimore, Maryland 21205, USA. mczink@jhmi.edulld:pubmed
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