| pubmed-article:18032037 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0226896 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0205531 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C1527415 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0020314 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C1412186 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0796679 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0935763 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:18032037 | lifeskim:mentions | umls-concept:C0723595 | lld:lifeskim |
| pubmed-article:18032037 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:18032037 | pubmed:dateCreated | 2008-1-9 | lld:pubmed |
| pubmed-article:18032037 | pubmed:abstractText | Beta-benzamido hydroxamic acids were discovered as potent TACE inhibitors. A computer model was constructed to help understanding the binding activities and guiding SAR study. SAR optimization led to the discovery of compound 30 which met all in vitro and in vivo criteria for the program and was selected for further evaluation. | lld:pubmed |
| pubmed-article:18032037 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18032037 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18032037 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18032037 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18032037 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:18032037 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:WassermanZeld... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:CovingtonMary... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:DeciccoCarl... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:TrzaskosJames... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:XueChu-BiaoCB | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:LiuRui-QinRQ | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:NewtonRobert... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:ChenLihuaL | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:ChristDavid... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:DuanJames... | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:LuZhonghuiZ | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:QianMingxinM | lld:pubmed |
| pubmed-article:18032037 | pubmed:author | pubmed-author:VaddiKrishnaK | lld:pubmed |
| pubmed-article:18032037 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18032037 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18032037 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:18032037 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18032037 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18032037 | pubmed:pagination | 241-6 | lld:pubmed |
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| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:meshHeading | pubmed-meshheading:18032037... | lld:pubmed |
| pubmed-article:18032037 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18032037 | pubmed:articleTitle | Discovery of beta-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors. | lld:pubmed |
| pubmed-article:18032037 | pubmed:affiliation | Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, USA. james.duan@bms.com | lld:pubmed |
| pubmed-article:18032037 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18032037 | lld:chembl |
