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pubmed-article:18029258pubmed:abstractTextCo-translational protein targeting by the signal recognition particle (SRP) relies on a complex series of structural rearrangements in the SRP and its receptor (SR). In order to precisely coordinate the individual steps, the GTPases of the SRP and the SR form a unique complex in which GTP hydrolysis is activated in a composite active site. A recent study provides new insights on the link between the GTPases and protein translocation.lld:pubmed
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pubmed-article:18029258pubmed:articleTitleProtein translocation: checkpoint role for SRP GTPase activation.lld:pubmed
pubmed-article:18029258pubmed:affiliationHeidelberg University Biochemistry Center (BZH), INF328, D-69120 Heidelberg, Germany.lld:pubmed
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