| pubmed-article:17984229 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C0038172 | lld:lifeskim |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C0004610 | lld:lifeskim |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C0042313 | lld:lifeskim |
| pubmed-article:17984229 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:17984229 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:17984229 | pubmed:dateCreated | 2007-12-31 | lld:pubmed |
| pubmed-article:17984229 | pubmed:abstractText | Limited data on the clinical outcome of vancomycin treatment compared with that of beta-lactam treatment in patients with methicillin-susceptible Staphylococcus aureus bacteremia (MSSA-B) are available. We used different and complementary approaches: (i) a retrospective cohort study using a propensity score to adjust for confounding by treatment assignment and (ii) a matched case-control study. Of all patients with S. aureus bacteremia (SAB) in two university-affiliated hospitals over a 7-year period, 294 patients with MSSA-B were enrolled in the cohort study. The cases for the case-control study were defined as patients who received vancomycin treatment for MSSA-B; the controls, who were patients that received beta-lactam treatment for MSSA-B, were selected at a 1:2 (case:control) ratio according to the objective matching scoring system and the propensity score system. In the cohort study, SAB-related mortality in patients with vancomycin treatment (37%, 10/27) was significantly higher than that in those with beta-lactam treatment (18%, 47/267) (P = 0.02). In addition, multivariate analysis revealed that vancomycin treatment was associated with SAB-related mortality when independent predictors for SAB-related mortality and propensity score were considered (adjusted odds ratio of 3.3, 95% confidence interval of 1.2 to 9.5). In the case-control study using the objective matching scoring system and the propensity score system, SAB-related mortality in case patients was 37% (10/27) and in control patients 11% (6/54) (P < 0.01). Our data suggest that vancomycin is inferior to beta-lactam in the treatment of MSSA-B. | lld:pubmed |
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| pubmed-article:17984229 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17984229 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17984229 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17984229 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17984229 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:17984229 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:KimEui-ChongE... | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:OhMyoung-donM... | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:KimSung-HanSH | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:KimHong-BinHB | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:ChoeKang-WonK... | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:KimNam-JoongN... | lld:pubmed |
| pubmed-article:17984229 | pubmed:author | pubmed-author:KimKye-HyungK... | lld:pubmed |
| pubmed-article:17984229 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17984229 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:17984229 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17984229 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17984229 | pubmed:pagination | 192-7 | lld:pubmed |
| pubmed-article:17984229 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:17984229 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:17984229 | pubmed:articleTitle | Outcome of vancomycin treatment in patients with methicillin-susceptible Staphylococcus aureus bacteremia. | lld:pubmed |
| pubmed-article:17984229 | pubmed:affiliation | Department of Internal Medicine, Seoul National University College of Medicine, 28 Youngundong, Chongrogu, Seoul 110-744, Republic of Korea. | lld:pubmed |
| pubmed-article:17984229 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17984229 | pubmed:publicationType | Clinical Trial | lld:pubmed |
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