pubmed-article:17983290 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17983290 | lifeskim:mentions | umls-concept:C0023185 | lld:lifeskim |
pubmed-article:17983290 | lifeskim:mentions | umls-concept:C0599851 | lld:lifeskim |
pubmed-article:17983290 | lifeskim:mentions | umls-concept:C0036341 | lld:lifeskim |
pubmed-article:17983290 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
pubmed-article:17983290 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:17983290 | pubmed:dateCreated | 2007-11-6 | lld:pubmed |
pubmed-article:17983290 | pubmed:abstractText | Twenty-seven schizophrenia spectrum patients and 25 healthy controls performed a probabilistic version of the serial reaction time task (SRT) that included sequence trials embedded within random trials. Patients showed diminished, yet measurable, sequence learning. Postexperimental analyses revealed that a group of patients performed above chance when generating short spans of the sequence. This high-generation group showed SRT learning that was similar in magnitude to that of controls. Their learning was evident from the very 1st block; however, unlike controls, learning did not develop further with continued testing. A subset of 12 patients and 11 controls performed the SRT in conjunction with positron emission tomography. High-generation performance, which corresponded to SRT learning in patients, correlated to activity in the premotor cortex and parahippocampus. These areas have been associated with stimulus-driven visuospatial processing. Taken together, these results suggest that a subset of patients who showed moderate success on the SRT used an explicit stimulus-driven strategy to process the sequential stimuli. This adaptive strategy facilitated sequence learning but may have interfered with conventional implicit learning of the overall stimulus pattern. | lld:pubmed |
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pubmed-article:17983290 | pubmed:language | eng | lld:pubmed |
pubmed-article:17983290 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:17983290 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:17983290 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:17983290 | pubmed:month | Nov | lld:pubmed |
pubmed-article:17983290 | pubmed:issn | 0894-4105 | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:AndreasenNanc... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:O'LearyDaniel... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:PontoLaura... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:JohnsonHans... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:TurnerBeth... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:MarvelCherie... | lld:pubmed |
pubmed-article:17983290 | pubmed:author | pubmed-author:PiersonRonald... | lld:pubmed |
pubmed-article:17983290 | pubmed:copyrightInfo | PsycINFO Database Record (c) 2007 APA, all rights reserved. | lld:pubmed |
pubmed-article:17983290 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:17983290 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:17983290 | pubmed:owner | NLM | lld:pubmed |