A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay.

Source:http://linkedlifedata.com/resource/pubmed/id/17976996

Bioorg. Med. Chem. 2008 Jan 15 16 2 822-9

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PMID
17976996