| pubmed-article:17950602 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17950602 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
| pubmed-article:17950602 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:17950602 | lifeskim:mentions | umls-concept:C1515999 | lld:lifeskim |
| pubmed-article:17950602 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:17950602 | pubmed:issue | 23 | lld:pubmed |
| pubmed-article:17950602 | pubmed:dateCreated | 2007-11-6 | lld:pubmed |
| pubmed-article:17950602 | pubmed:abstractText | Several 1,8-naphthyridine-3-carboxamide derivatives (8-23) were synthesized and tested for in vitro cytotoxicity against eight cancer cell lines and a normal cell line. Compound 12 exhibited high cytotoxicity (IC(50)=1.37microM) in HBL-100 (breast) cell line while compounds 17 (IC(50)=3.7microM) and 22 (IC(50)=3.0microM) have shown high cytotoxicity in KB (oral) and SW-620 (colon) cell lines, respectively. The synthesized 1,8-naphthyridine-3-carboxamides were also evaluated for anti-inflammatory and myeloprotective activities, indicated by modulation in cytokine and chemokine levels secreted by dendritic cells. | lld:pubmed |
| pubmed-article:17950602 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17950602 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17950602 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17950602 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17950602 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17950602 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17950602 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17950602 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17950602 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:17950602 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:SrivastavaSan... | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:MukherjeeRama... | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:JaggiManuM | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:BurmanAnand... | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:AgarwalShiv... | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:SinghAnu TAT | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:MadanAlkaA | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:RaniNidhiN | lld:pubmed |
| pubmed-article:17950602 | pubmed:author | pubmed-author:VishnoiManupr... | lld:pubmed |
| pubmed-article:17950602 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17950602 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:17950602 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:17950602 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17950602 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17950602 | pubmed:pagination | 6660-4 | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:meshHeading | pubmed-meshheading:17950602... | lld:pubmed |
| pubmed-article:17950602 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17950602 | pubmed:articleTitle | Anticancer and anti-inflammatory activities of 1,8-naphthyridine-3-carboxamide derivatives. | lld:pubmed |
| pubmed-article:17950602 | pubmed:affiliation | Division of Medicinal Chemistry, Dabur Research Foundation, 22, Site IV, Sahibabad, Ghaziabad, 201 010 UP, India. | lld:pubmed |
| pubmed-article:17950602 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17950602 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17950602 | lld:chembl |
