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pubmed-article:17947484pubmed:abstractTextPertuzumab, a first-in-class human epidermal receptor 2 (HER2) dimerization inhibitor, is a humanized monoclonal anti-HER2 antibody that binds HER2's dimerization domain and inhibits HER2 signaling. Based on supporting preclinical studies, we undertook a Phase II trial of pertuzumab in patients with recurrent non-small cell lung cancer (NSCLC).lld:pubmed
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pubmed-article:17947484pubmed:articleTitleEfficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non small cell lung cancer.lld:pubmed
pubmed-article:17947484pubmed:affiliationThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.lld:pubmed
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